Bing Predicts winner: Rams (58 percent)
Opening line: LA -3
Kickoff time: 4:25 p.m. EST (Saturday)
This game is unwatchable for anyone who isn't a diehard 49ers or Rams fan. The Rams might be without Jared Goff after the rookie took a vicious hit from Richard Sherman in last week's 24-3 loss in Seattle. If Goff is unavailable, Sean Mannion would be next in line to start, and he'd get the chance to face the league's worst defense. For what it's worth, San Francisco blew out Los Angeles way back in Week 1 in a 28-0 win. Since then, the 49ers have lost 13 straight.